> For the complete documentation index, see [llms.txt](https://vci-gci-docs.clinicalgenome.org/vci-gci-docs/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://vci-gci-docs.clinicalgenome.org/vci-gci-docs/vci-help/publishing-from-the-vci/publishing-to-clinvar.md). # Publishing to ClinVar ### [ClinVar](https://www.ncbi.nlm.nih.gov/clinvar/) VCI users curating as part of **any affiliation** can use the "ClinVar Submission" buttons on their approved interpretation snapshot to generate data that can be submitted to ClinVar via spreadsheet. The **Batch Submission** option was introduced in November 2022. {% hint style="danger" %} Batch submission does not auto-submit variants to ClinVar from the VCI. It is used to generate a ClinVar submission file which must then be downloaded and submitted to ClinVar. {% endhint %}
#### Batch submission process Click on **Add to Current Batch** to add a variant to a batch Note, if this is the first variant added, a new batch will be created and named with current month and year The "Add" button will change to a "Remove" button The batch name will be added to the Publishing Status for the variant.
Click on the **Batch name** to view the current and closed ClinVar Submission Batches for the Affiliation.
Once all desired variants have been added to the batch, click **Generate Submission Data,** which opens the **ClinVar Submission Data** window. Click **Generate**. Once the data populates, click **Copy (to clipboard)**. The data can now be pasted into a spreadsheet and submitted in the ClinVar submission portal. Once the data has been submitted to ClinVar, click the **Edit** button to open the Edit Current Batch window. Change the Status from "In Progress" to "Submitted to ClinVar." The Date Submitted field will now be available to edit and a Warning will appear. You must type "Confirm" into the text box to proceed. Then click the **Save** button to close the batch. The submission batch will now be listed under Closed Batches on the affiliation's ClinVar Submission Batches page. The Publishing Status of all variants in the batch will be updated to "Closed Batches."

Move the cursor over "Closed Batches" to display the batch name.

--- # Agent Instructions This documentation is published with GitBook. GitBook is the documentation platform designed so that both humans and AI agents can read, navigate, and reason over technical content effectively. Learn more at gitbook.com. ## Querying This Documentation If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question. Perform an HTTP GET request on the current page URL with the `ask` query parameter, and the optional `goal` query parameter: ``` GET https://vci-gci-docs.clinicalgenome.org/vci-gci-docs/vci-help/publishing-from-the-vci/publishing-to-clinvar.md?ask=&goal= ``` `ask` is the immediate question: it should be specific, self-contained, and written in natural language. `goal` is optional and describes the broader end goal you are ultimately trying to accomplish on behalf of the user. GitBook uses it to tailor the answer towards what is most useful for that goal. The response will contain a direct answer to the question and relevant excerpts and sources from the documentation. Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.