Adding Curated Evidence

Following the evaluation of each criterion (or group of criteria), curators may include associated Curated Evidence.

• The Population, Variant Type, and Experimental tabs include fields to add Curated Literature Evidence by PMID.

• The Case/Segregation tab () includes Curated Evidence fields which allow for additional types of evidence (e.g. Clinical Lab).

Add Curated Literature Evidence

Navigate to the criteria evaluation to which you wish to add literature evidence.

Click "Add PMID" to open the "Add new PubMed Article" selection screen.

Enter PMID and click "Retrieve PubMed Article."

Confirm the retrieved citation is correct and click "Add Article."

The citation will now appear under Curated Literature Evidence.

Select the appropriate criteria code from the pulldown menu and enter a description of relevant data in the "Evidence" text box.

Click "Add Evidence". Note, both fields must be completed to proceed.

The literature evidence is now added to the evaluation along with the curator's name (and affiliation if applicable) and date/time added.

If you wish to change the criteria code or revise the evidence text summary, click Edit.

If you would like to remove the article completely, click Delete. You will be prompted to confirm deletion and have the option to cancel if you clicked delete in error.

You may now move on to evaluate other criteria, or click Add PMID to add additional article(s) to this section.