> For the complete documentation index, see [llms.txt](https://vci-gci-docs.clinicalgenome.org/vci-gci-docs/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://vci-gci-docs.clinicalgenome.org/vci-gci-docs/gci-help/saving-reviewing-and-approving-classifications/approving-a-gene-disease-record.md). # Approving a Gene-Disease Record After the expert panel has met and voted to approve the gene-disease record, the provisional record can be approved in the GCI. When your saved Provisional record is ready to be approved, either select the "View/Approve Current Provisional" button in the "My classification" section of the Curation Central page: ![](https://453646021-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FzjRMfxI6chghHwy4VhQv%2Fuploads%2FVhe3pejEqp43AgPfcchx%2FScreen%20Shot%202022-06-17%20at%203.15.55%20PM.png?alt=media\&token=240cea3e-a9aa-4232-ae2e-82c643277be9) or select the "Approve" button at the bottom of the Classification Summary page: ![](https://453646021-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FzjRMfxI6chghHwy4VhQv%2Fuploads%2FCzhaqUrkKTJvlFmnnEwY%2FScreen%20Shot%202022-06-17%20at%203.22.04%20PM.png?alt=media\&token=daab2568-f266-429c-b548-cc88c1f746b4) Both options will bring up a new panel. If you need to acknowledge other contributors (e.g. other GCEPs), select the button, which will expand the section of the panel and enables you to enter additional contributors. Guidance on acknowledging other contributors can be found in Appendix D of the [SOP](https://www.clinicalgenome.org/docs/gene-disease-validity-standard-operating-procedure-version-9/). ![](https://453646021-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FzjRMfxI6chghHwy4VhQv%2Fuploads%2FasmrXDB3Dk9k1GZsmYea%2FScreen%20Shot%202022-08-15%20at%203.53.54%20PM.png?alt=media\&token=8f5e83a0-4029-4081-a8b3-e234507fd9a3) To approve a classification, you must enter the final approval date. This should be the date on which the GCEP has voted to approve the gene-disease classification and can predate the date the approval is saved in the GCI. If curation was performed using criteria from an older version of the SOP, you can select it from the drop-down menu. The current version is shown by default. ![](https://453646021-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FzjRMfxI6chghHwy4VhQv%2Fuploads%2FaLeTUSXwIsKB1hKMQ0px%2FScreen%20Shot%202022-08-15%20at%203.43.23%20PM.png?alt=media\&token=706b7649-4e13-4a04-962d-34a780fabe56) Once you select "Preview Approval," you will be able to see the information (date, approver, additional comments etc.) for the Approval. Selecting "Submit Approval" will save the record as "Approved". ![](https://453646021-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FzjRMfxI6chghHwy4VhQv%2Fuploads%2F288Cy8BIa01ZqYWWubFJ%2FScreen%20Shot%202022-06-17%20at%203.31.55%20PM.png?alt=media\&token=32f4d7ee-10c7-4567-87d2-781ed8cded87) After submitting/saving the approval, a panel providing the option to publish the gene-disease record will appear (see following section). The "Saved Provisional and Approved Classification(s)" panel below shows all saved classifications for the gene-disease record; the newly approved classification will be marked with a green flag indicating that it is the most current approved record. Selecting the "Approved Summary" link will open a new page or tab that shows the current Evidence Summary for the saved classification. ![](https://453646021-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FzjRMfxI6chghHwy4VhQv%2Fuploads%2FSZxwcwuaVClxBf7fbUe3%2FScreen%20Shot%202022-06-17%20at%203.42.19%20PM.png?alt=media\&token=9cdaa3be-545d-4ae4-a916-0eb22fcb354d) Below the Curation Central header panel, the central panel will now show the Approved classification; the "View Current Approved" button opens a new window or tab with the approved Evidence Summary. ![](https://453646021-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FzjRMfxI6chghHwy4VhQv%2Fuploads%2FbX9W692JkvKLHK3o4jVo%2FScreen%20Shot%202022-06-17%20at%203.56.26%20PM.png?alt=media\&token=b96980b9-2510-4240-9802-ae81476f2e1c) {% hint style="info" %} Once an Approved Classification is submitted, it can not be edited. It will remain viewable and can be published if no further changes are needed. However, the curation interface will remain active -- new evidence can be added and existing evidence can be edited. Updated Summary Classifications can be saved and submitted as a new Provisional and Approved classifications. The prior Provisional and Approved classifications will then be archived. {% endhint %} --- # Agent Instructions This documentation is published with GitBook. GitBook is the documentation platform designed so that both humans and AI agents can read, navigate, and reason over technical content effectively. Learn more at gitbook.com. ## Querying This Documentation If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question. Perform an HTTP GET request on the current page URL with the `ask` query parameter, and the optional `goal` query parameter: ``` GET https://vci-gci-docs.clinicalgenome.org/vci-gci-docs/gci-help/saving-reviewing-and-approving-classifications/approving-a-gene-disease-record.md?ask=&goal= ``` `ask` is the immediate question: it should be specific, self-contained, and written in natural language. `goal` is optional and describes the broader end goal you are ultimately trying to accomplish on behalf of the user. GitBook uses it to tailor the answer towards what is most useful for that goal. The response will contain a direct answer to the question and relevant excerpts and sources from the documentation. Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.