General Navigation

Landing Page

When you first login, you will be on the landing page, which contains general information about ClinGen and the VCI and GCI. To access your curations, head to the dashboard.

Dashboard View

Default Dashboard View with My Interpretations Tables
All Variant Interpretations Table
All Gene-Disease Records Table

Available from all pages. From here you can:

Access the variant prioritization tool

Initiate a new variant curation

Initiate a new gene curation; disabled (grayed out) if not logged in to a ClinGen GCEP affiliation

Return to the dashboard

Access help resources. Pulldown menu options include links to this documentation, GCI and VCI SOPs, Terms of Use/User Agreement, GeneTracker tool (requires separate login), and email helpdesk.

Log out of the interface

Affiliation Bar

Available from all pages. Displays current affiliation. Click to change the affiliation you are curating under.

On the Test site, all users can select "Test Site Example Affiliation" to access the GCI

Displays the account and affiliation you are logged in under.

Tool Bar

To select which curation table(s) to display on the dashboard.

All Variant Interpretations – This list contains all Interpretations curated to date, by all users/affiliations, along with disease/mode of inheritance, and date created.

My Variant and Gene Interpretations - These tables list all VCI and GCI entries for the user or logged-in affiliation.

All Gene-Disease Records – This list contains all the Gene-Disease Records curated to date, by all users/affiliations, along with disease/mode of inheritance, and date created.

My ClinVar Submission Batches - This displays both current and closed ClinVar submission batches for the selected affiliation. Note: This option only appears when logged into an affiliation.

Curation Tables

  • By default, the dashboard will open to My Variant and Gene Interpretations.

  • All tables have similar functionality. Users can:

    • Search/filter on any text in any text field

    • Download the table as a .csv file

    • Navigate with pagination features and expand the number of curations displayed at once (up to 100)

  • The My Variant Interpretations and My Gene-Disease Records tables have additional detail and functionality.

    • Columns for status, classification, met criteria (variant only), and date last modified

    • Ability to filter by status (In Progress, Provisional, Approved and Published)

Search tips:

Not case-sensitive

No wild cards search features

Total count updates and table rows filter as you type

Begin Curation

For assistance with the VCI, click Next, or go to:

VCI Help

For assistance with the GCI, go to:

GCI Help

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