After the expert panel has met and voted to approve the gene-disease record, the provisional record can be approved in the GCI.
When your saved Provisional record is ready to be approved, either select the "View/Approve Current Provisional" button in the "My classification" section of the Curation Central page:
or select the "Approve" button at the bottom of the Classification Summary page:
Both options will bring up a new panel. If you need to acknowledge other contributors (e.g. other GCEPs), select the button, which will expand the section of the panel and enables you to enter additional contributors. Guidance on acknowledging other contributors can be found in Appendix D of the SOP.
To approve a classification, you must enter the final approval date. This should be the date on which the GCEP has voted to approve the gene-disease classification and can predate the date the approval is saved in the GCI. If curation was performed using criteria from an older version of the SOP, you can select it from the drop-down menu. The current version is shown by default.
Once you select "Preview Approval," you will be able to see the information (date, approver, additional comments etc.) for the Approval. Selecting "Submit Approval" will save the record as "Approved".
After submitting/saving the approval, a panel providing the option to publish the gene-disease record will appear (see following section). The "Saved Provisional and Approved Classification(s)" panel below shows all saved classifications for the gene-disease record; the newly approved classification will be marked with a green flag indicating that it is the most current approved record. Selecting the "Approved Summary" link will open a new page or tab that shows the current Evidence Summary for the saved classification.
Below the Curation Central header panel, the central panel will now show the Approved classification; the "View Current Approved" button opens a new window or tab with the approved Evidence Summary.
Once an Approved Classification is submitted, it can not be edited. It will remain viewable and can be published if no further changes are needed. However, the curation interface will remain active -- new evidence can be added and existing evidence can be edited. Updated Summary Classifications can be saved and submitted as a new Provisional and Approved classifications. The prior Provisional and Approved classifications will then be archived.
